Dioxaphetyl butyrate

Dioxaphetyl butyrate
Clinical data
Other names	Amidalgon, Spasmoxal
Routes of; administration	Oral, Other ROA Unknown
ATC code	none;
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class A1 (Narcotic drugs); CA: Schedule I; DE: Anlage I (Authorized scientific use only); US: Schedule I;
Identifiers
	IUPAC name Ethyl 4-morpholin-4-yl-2,2-di(phenyl)butanoate;
CAS Number	467-86-7 ;
PubChem CID	48194;
ChemSpider	43838 ;
UNII	G751H98FY4;
KEGG	D12699 ;
CompTox Dashboard (EPA)	DTXSID20196914 ;
ECHA InfoCard	100.006.731
Chemical and physical data
Formula	C22H27NO3
Molar mass	353.462 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC(=O)C(CCN1CCOCC1)(c1ccccc1)c1ccccc1;
	InChI InChI=1S/C22H27NO3/c1-2-26-21(24)22(19-9-5-3-6-10-19,20-11-7-4-8-12-20)13-14-23-15-17-25-18-16-23/h3-12H,2,13-18H2,1H3 ; Key:LQGIXNQCOXNCRP-UHFFFAOYSA-N ;
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Dioxaphetyl butyrate (INN; trade names Amidalgon, Spasmoxal) is an opioid analgesic which is a diphenylacetic acid derivative, related to other open-chain opioid drugs such as dextropropoxyphene, levacetylmethadol (LAAM), lefetamine and dimenoxadol.^[2]^[3]

It produces similar effects to other opioids, including dependence, euphoria, analgesia, sedation, constipation, dizziness and nausea.^[4]

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9621 and a 2013 annual aggregate manufacturing quota of zero.^[5]

References

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ "Dioxaphetyl butyrate". PubChem. U.S. National Library of Medicine. Retrieved 2019-06-03.
^ "Dioxaphetyl butyrate | C22H27NO3". ChemSpider. Retrieved 2019-06-03.
^ "Dioxaphetyl butyrate". drugcentral.org. Retrieved 2019-06-03.
^ "Misuse of Drugs Act : Legislative history · Part I Class A · Section 1(a): Explicitly named Class A substances". isomerdesign.com. Retrieved 2019-06-03.

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[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[2] "Dioxaphetyl butyrate". PubChem. U.S. National Library of Medicine. Retrieved 2019-06-03.

[3] "Dioxaphetyl butyrate | C22H27NO3". ChemSpider. Retrieved 2019-06-03.

[4] "Dioxaphetyl butyrate". drugcentral.org. Retrieved 2019-06-03.

[5] "Misuse of Drugs Act : Legislative history · Part I Class A · Section 1(a): Explicitly named Class A substances". isomerdesign.com. Retrieved 2019-06-03.

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Dioxaphetyl butyrate

References

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